Agentic AI and Autonomous Agents: Transforming Artificial Intelligence
Agentic AI and autonomous agents represent a major shift in artificial intelligence, moving from passive, rule-based systems to autonomous, goal-driven entities capable of independent decision-making, learning, and adaptation with minimal human oversight. This rise is reshaping industries, research, and society.
Defining Features and Technological Foundations
- Agentic AI refers to systems that autonomously set, pursue, and adapt complex goals, demonstrating advanced decision-making, adaptability, and self-sufficiency (Acharya et al., 2025; Murugesan & Murugesan, 2025; Viswanathan, 2025; Erukude et al., 2025).
- Autonomous agents sense their environment, plan and execute actions, learn from experience, and often collaborate with other agents or humans (Negnevitsky, 2025; Dodig-Crnkovic & Burgin, 2024; Sun & Botev, 2021; Wang et al., 2023).
- Recent advances leverage large language models (LLMs), deep reinforcement learning, and multi-modal reasoning, enabling agents to perform diverse, complex tasks in dynamic environments (Barua, 2024; Erukude et al., 2025; Wang et al., 2023; Zhou et al., 2023).
Applications and Impact
| Domain | Example Applications | Citations |
|---|---|---|
| Healthcare | Adaptive treatment planning, disease diagnosis | (Acharya et al., 2025; Hughes et al., 2025; Negnevitsky, 2025; Barua, 2024) |
| Finance | Automated trading, risk assessment | (Acharya et al., 2025; Negnevitsky, 2025; Dodig-Crnkovic & Burgin, 2024) |
| Cloud/IT | Self-managing cloud systems, auto-remediation | (Karanam, 2025; Acharya et al., 2025) |
| Robotics/IoT | Autonomous vehicles, smart manufacturing | (Dodig-Crnkovic & Burgin, 2024; Wang et al., 2023; Patel et al., 2025) |
| Customer Service | Virtual assistants, automated support | (Barua, 2024; Sun & Botev, 2021; Zhou et al., 2023) |
| Scientific Research | Automated discovery, simulation | (Negnevitsky, 2025; Erukude et al., 2025; Wang et al., 2023) |
Figure 1: Key domains and applications of agentic AI and autonomous agents.
Challenges and Future Directions
- Ethical and Societal Concerns: Ensuring goal alignment, transparency, accountability, and trust are critical as agents gain autonomy (Acharya et al., 2025; Murugesan & Murugesan, 2025; Hughes et al., 2025; Viswanathan, 2025; Deng et al., 2024).
- Technical Hurdles: Robustness, generalization, explainability, and security remain open research areas (Patel et al., 2025; Deng et al., 2024; Zhou et al., 2023).
- Evaluation: Benchmarks like AgentBench and WebArena reveal current agents lag behind human performance in real-world tasks, highlighting the need for further development (Barua, 2024; Zhou et al., 2023; Wang et al., 2023).
Conclusion
Agentic AI and autonomous agents are rapidly advancing, offering transformative potential across sectors. However, realizing their benefits safely and ethically requires continued research into governance, transparency, and robust technical solutions. Their integration marks a new era in AI—one defined by collaboration, adaptability, and intelligent autonomy.
References
Acharya, D., Kuppan, K., & Bhaskaracharya, D. (2025). Agentic AI: Autonomous Intelligence for Complex Goals—A Comprehensive Survey. IEEE Access, 13, 18912-18936. https://doi.org/10.1109/access.2025.3532853
Murugesan, S., & Murugesan, S. (2025). The Rise of Agentic AI: Implications, Concerns, and the Path Forward. IEEE Intelligent Systems, 40, 8-14. https://doi.org/10.1109/mis.2025.3544940
Hughes, L., Dwivedi, Y., Malik, T., Shawosh, M., Albashrawi, M., Jeon, I., Dutot, V., Appanderanda, M., Crick, T., De’, R., Fenwick, M., Gunaratnege, S., Jurcys, P., Kar, A., Kshetri, N., Li, K., Mutasa, S., Samothrakis, S., Wade, M., & Walton, P. (2025). AI Agents and Agentic Systems: A Multi-Expert Analysis. Journal of Computer Information Systems, 65, 489 - 517. https://doi.org/10.1080/08874417.2025.2483832
Negnevitsky, M. (2025). The Rise of Autonomous AI Agents: Automating Complex Tasks. International Journal of Artificial Intelligence for Science (IJAI4S). https://doi.org/10.63619/ijai4s.v1i2.007
Dodig-Crnkovic, G., & Burgin, M. (2024). A Systematic Approach to Autonomous Agents. Philosophies. https://doi.org/10.3390/philosophies9020044
Viswanathan, P. (2025). AGENTIC AI: A COMPREHENSIVE FRAMEWORK FOR AUTONOMOUS DECISION-MAKING SYSTEMS IN ARTIFICIAL INTELLIGENCE. INTERNATIONAL JOURNAL OF COMPUTER ENGINEERING AND TECHNOLOGY. https://doi.org/10.34218/ijcet_16_01_069
Patel, A., Patel, H., & Patel, C. (2025). A Survey on the Evolution of Autonomous Agents: Trends, Challenges, and Future Directions. SPU- Journal of Science, Technology and Management Research. https://doi.org/10.63766/spujstmr.24.000033
Barua, S. (2024). Exploring Autonomous Agents through the Lens of Large Language Models: A Review. ArXiv, abs/2404.04442. https://doi.org/10.48550/arxiv.2404.04442
Sun, N., & Botev, J. (2021). Intelligent autonomous agents and trust in virtual reality. Computers in Human Behavior Reports. https://doi.org/10.1016/j.chbr.2021.100146
Erukude, S., Veluru, S., & Marella, V. (2025). AGENTIC AI - THE RISE OF AUTONOMOUS INTELLIGENT AGENTS IN THE ERA OF LLMS. Indian Journal of Computer Science and Engineering. https://doi.org/10.21817/indjcse/2025/v16i1/251602024
Wang, L., , C., Feng, X., Zhang, Z., Yang, H., Zhang, J., Chen, Z., Tang, J., Chen, X., Lin, Y., Zhao, W., Wei, Z., & Wen, J. (2023). A Survey on Large Language Model based Autonomous Agents. Frontiers Comput. Sci., 18, 186345. https://doi.org/10.1007/s11704-024-40231-1
Deng, Z., Guo, Y., Han, C., , W., Xiong, J., Wen, S., & Xiang, Y. (2024). AI Agents Under Threat: A Survey of Key Security Challenges and Future Pathways. ACM Computing Surveys, 57, 1 - 36. https://doi.org/10.1145/3716628
Karanam, V. (2025). Autonomous agents in the cloud: Advancing application management with agentic AI. World Journal of Advanced Research and Reviews. https://doi.org/10.30574/wjarr.2025.26.2.2122
Zhou, S., Xu, F., Zhu, H., Zhou, X., Lo, R., Sridhar, A., Cheng, X., Bisk, Y., Fried, D., Alon, U., & Neubig, G. (2023). WebArena: A Realistic Web Environment for Building Autonomous Agents. ArXiv, abs/2307.13854. https://doi.org/10.48550/arxiv.2307.13854
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